Abstract: This review examines some of the current perspectives in evidencebased laboratory medicine. From evidence-based medicine, which has concentrated mainly on treatments, we have learned that systematic reviews of the literature are the major way of producing high-quality evidence. This is because systematic reviews search all the literature, apply quality standards to ensure that only the best evidence is available, and aggregate a sufficient weight of information to inform on both the direction of a result (that a treatment works) and the magnitude of the result (how good the treatment is). In laboratory medicine, we have few systematic reviews. Even those we do have give little …
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